When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

40 Years of Progress: Transforming Cancer. Saving Lives.

The AICR Lifestyle & Cancer Symposium addresses the most current and consequential issues regarding diet, obesity, physical activity and cancer.

The Annual AICR Research Conference is the most authoritative source for information on diet, obesity, physical activity and cancer.

Cancer Update Program – unifying research on nutrition, physical activity and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

Are you ready to make a difference? Join our team and help us advance research, improve cancer education and provide lifesaving resources.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

AICR is committed to putting what we know about cancer prevention into action. To help you live healthier, we’ve taken the latest research and made 10 Cancer Prevention Recommendations.

Research Projects > 2008 Grantees

Transcriptional Attenuation Induced by Sodium Butyrate and Vitamin D3 in Colon Cancer Cells

Project Description

Vitamin D and sodium butyrate, generated by the fermentation of dietary fiber are both regulators of colon maturation and gene expression. They regulate gene expression through a process called transcriptional attenuation. Since the mechanisms of transcriptional attenuation are largely unknown this study sought to examine and characterize the candidate genes for transcriptional attenuation using a novel, custom built microarray analysis to understand the nature and regulatory mechanisms recruited by two nutritional factors that coordinate colonic cell maturation.

Leave a Reply

Your email address will not be published. Required fields are marked *

More News & Updates

Close