Prostate cancer is the second most common cancer among men worldwide. Prostate cancer is more common as men age.
In the U.S. 97% of all prostate cancers are diagnosed in men 50 years or older. The prostate is a walnut sized gland in men that surrounds the top of the urethra just below the bladder outlet; it produces seminal fluid. Male hormones, such as testosterone, control its growth and function.
AICR’S latest report on prostate cancer found that maintaining a healthy weight is the best thing you can do to lower your cancer risk.
Lifestyle and prostate cancer risk.
There is strong evidence that being overweight or obese increases the risk of advanced prostate cancer.
- Obesity influences the levels of a number of hormones and growth factors. Insulin and leptin are elevated in people with obesity and can promote the growth of cancer cells.
- Sex steroid hormones, including estrogen, androgen, and progesterone, are likely to play a role in obesity and cancer. In men, obesity is related to lower serum testosterone levels, which in turn may be associated with enhanced risk of or adverse outcome in advanced prostate cancer.
- Obesity is characterized by a low-grade chronic inflammatory state. Such chronic inflammation can promote cancer development.
There is strong evidence that developmental factors in the womb, childhood, and adolescence that influence growth are linked to an increased risk of prostate cancer.
The science of survival.
AICR’s health guides and recommendations are developed from research that focuses on how nutrition and lifestyle affect the prevention, treatment, and survival of cancer. Paramount to our updates is the Continuous Update Project which helps you stay on top of new findings, and understand the data that sits at the center of our work.