Project Description
During the previous funding period, Dr. Fong obtained data to demonstrate that esophageal tumor incidence was 100% in the zinc deficient versus 23% and 7% in the zinc sufficient and ad libitum pair fed rats. She found that prolonged cell proliferation induced by zinc deficiency can lead to esophageal tumorigenesis. Dr. Fong continued her biochemical analysis of tissues collected to further clarify the relationship of zinc to carcinogenesis.