When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

40 Years of Progress: Transforming Cancer. Saving Lives.

The AICR Lifestyle & Cancer Symposium addresses the most current and consequential issues regarding diet, obesity, physical activity and cancer.

The Annual AICR Research Conference is the most authoritative source for information on diet, obesity, physical activity and cancer.

Cancer Update Program – unifying research on nutrition, physical activity and cancer.

ResourcesNav New164

Whether you are a healthcare provider, a researcher, or just someone who wants to learn more about cancer prevention, we’re here to help.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

Are you ready to make a difference? Join our team and help us advance research, improve cancer education and provide lifesaving resources.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

Research Projects > 2009 Grantees

The Role of Dietary Fiber and Gut Microflora in Prevention of Colorectal Cancer

Project Description

This study investigated the mechanistic link between dietary fiber, gut microflora, butyrate, and DNA/histone modifications that result in gene expression changes that alter colorectal cancer susceptibility. An inbred strain of genetically-identical mice were maintained with or without intestinal bacteria and provided with two high-fiber diets that produced different levels of butyrate and a low-fiber control diet. A carcinogen was used to induce cancer, and butyrate levels and the number/size of colorectal tumors were scored.

Leave a Reply

Your email address will not be published. Required fields are marked *

More News & Updates