When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

The Continuous Update Project (CUP) is an ongoing program that analyzes global research on how diet, nutrition and physical activity affect cancer risk and survival.

A major milestone in cancer research, the Third Expert Report analyzes and synthesizes the evidence gathered in CUP reports and serves as a vital resource for anyone interested in preventing cancer.

AICR has pushed research to new heights, and has helped thousands of communities better understand the intersection of lifestyle, nutrition, and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

AICR is committed to putting what we know about cancer prevention into action. To help you live healthier, we’ve taken the latest research and made 10 Cancer Prevention Recommendations.

Research Projects > 2007 Grantees

Role of MLH1 Promoter, SNP and Diet in Colon Cancer

Project Description

This study examined how dietary factors interact with the MLHI-93GA promoter SNP functions and affect the etiology of microsatellite instability positive and negative, microsatellite stable colorectal tumors. Colorectal cancer cases from Ontario, Newfoundland and Seattle were included and cell studies used colorectal cancer cell lines. These studies helped to better understand how dietary factors can regulate the contribution of the MLHI-93GA polymorphism to colorectal cancer susceptibility at the population level.

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