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Research Projects > 2010 Grantees

GPx-1 Polymorphisms, Selenium and Cancer

Project Description

This cell study is examining the hypothesis that individual differences in the gene sequence of a selenium-containing enzyme (GPx-1) determine how the enzyme interacts with selenium and its effectiveness in protecting cells from DNA damage that could lead to mutations and eventually result in cancer. The experiments plan on indicating the amount of dietary selenium certain individuals or subpopulations need for the greatest cancer-protective benefits.

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