When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

The Continuous Update Project (CUP) is an ongoing program that analyzes global research on how diet, nutrition and physical activity affect cancer risk and survival.

A major milestone in cancer research, the Third Expert Report analyzes and synthesizes the evidence gathered in CUP reports and serves as a vital resource for anyone interested in preventing cancer.

Whether you are a healthcare provider, a researcher, or just someone who wants to learn more about cancer prevention, we’re here to help.

AICR has pushed research to new heights, and has helped thousands of communities better understand the intersection of lifestyle, nutrition, and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

AICR is committed to putting what we know about cancer prevention into action. To help you live healthier, we’ve taken the latest research and made 10 Cancer Prevention Recommendations.

Research Projects > 1994 Grantees

Fatty Acids, Mitochrondia and Molecular Genetics of Colon Cancer

Project Description

Dr. Augenlicht continued his investigations on the molecular mechanisms by which dietary fibers reduce the risk for development of colon cancer. He observed that short chain fatty acids (SCFAs) produced by bacteria from dietary fiber in the colon alter the expression of several mitochondrial genes in colonic epithelial cells. Dr. Augenlicht sought determine how two of the major genetic alterations occurring in colonic carcinomas (APC gene and DCC gene) respond to the natural inducers of differentiation, SCFAs and in particular, butyrate.

Leave a Reply

Your email address will not be published. Required fields are marked *

More News & Updates

Close