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Research Projects > 2009 Grantees

Dietary Induced Sporadic Colon Cancer

Project Description

Much colon cancer is linked to consumption of diets that subtly alter the normal balance of the colonic mucosa and elevate the probability of a tumor forming over a long period of time. This study used a novel mouse model to examine the mechanism by which the Wnt signaling pathway is altered by nutritional factors present in a western diet (high in fat and low calcium, vitamin D, choline, methionine, folate and fiber).

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