When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

The Continuous Update Project (CUP) is an ongoing program that analyzes global research on how diet, nutrition and physical activity affect cancer risk and survival.

A major milestone in cancer research, the Third Expert Report analyzes and synthesizes the evidence gathered in CUP reports and serves as a vital resource for anyone interested in preventing cancer.

AICR has pushed research to new heights, and has helped thousands of communities better understand the intersection of lifestyle, nutrition, and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

AICR is committed to putting what we know about cancer prevention into action. To help you live healthier, we’ve taken the latest research and made 10 Cancer Prevention Recommendations.

Research Projects > 2008 Grantees

Chemoprevention of HER2/NEU Overexpressing Breast Cancer

Project Description

Conjugated linoleic acid (CLA), a family of fatty acids, occurring in dairy products and ruminant meat is a potent inhibitor of mammary carcinogenesis in rats. This study focused on elucidation of the mechanisms for the tumourigenesis stimulatory effects of t10,c12-CLA on erbB2/her2/neu overexpressing mammary epithelium in mice. It investigated the role of stromal-epithelium interactions, the possible role of IGF-1/insulin receptor mediated signal route, and examined the PI3K/AKT/mTOR/CXC4 signal pathway.

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