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The Continuous Update Project (CUP) is an ongoing program that analyzes global research on how diet, nutrition and physical activity affect cancer risk and survival.

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AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

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Research Projects > 1993 Grantees

A Case-Control Study of Risk Factors for Gastric Cancer in Three Geographic Areas of Mexico

Project Description

People in Mexico who eat hot chili peppers have five times higher rates of gastric cancer than non-chili eating people. Capsaicin, the ingredient that makes peppers taste hot, is thought to be the culprit. Moreover, the gastric infection, by Helicobacter pylori, is also thought to play a role in gastric cancer. Dr. Lopez-Carrillo studied this issue using a food questionnaire and blood samples from volunteers in various regions of Mexico. Resolution of this question could result in possibly recommending eliminating hot chili peppers from the Mexican diet and potentially decreasing gastric cancer incidence by nearly 70%.

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