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Vitamin Intervention in Smokers (1995)


Vitamin Intervention in Smokers

Key words:

smokers, vitamin C, vitamin E, bet-carotene, polycyclic aromatic hydrocarbon adducts

Research Institution:

Columbia University


New York


Regina M Santella

Project Description:

Dr. Santella conducted a vitamin intervention study in smokers who took either vitamin C, vitamin E, and beta-carotene or a placebo. Polycyclic aromatic hydrocarbon (PAH)-DNA adducts, an intermediate end point for smoking-induced genotoxic damage, was measured in mononuclear cells and correlated to plasma vitamin levels in order to determine the possible protective effects of these antioxidant vitamins.

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