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AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

40 years of progress

Fighting for a better future

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When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

40 Years of Progress: Transforming Cancer. Saving Lives.

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Cancer Update Program – unifying research on nutrition, physical activity and cancer.

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Whether you are a healthcare provider, a researcher, or just someone who wants to learn more about cancer prevention, we’re here to help.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

Research Projects > 1993 Grantees

Attenuation of Cancer Cachexia by Reduction of TNF and IL-1 Productions

Project Description

TNF? and IL-1? play an active role in the cancer process by suppressing appetite, inducing sleepiness, fever, pain, and breaking down fat and muscle tissue in cancer patients. Curcumin, a component of curry and an antioxidant, reduces the production of TNF? and IL-1? in a leukemia cell line. Dr. Chan studied a variety of spices and herbs to see if they would inhibit TNF? and IL-1? and studied the mechanisms by which this occurs in a mouse model.

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