When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

The Continuous Update Project (CUP) is an ongoing program that analyzes global research on how diet, nutrition and physical activity affect cancer risk and survival.

A major milestone in cancer research, the Third Expert Report analyzes and synthesizes the evidence gathered in CUP reports and serves as a vital resource for anyone interested in preventing cancer.

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AICR has pushed research to new heights, and has helped thousands of communities better understand the intersection of lifestyle, nutrition, and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

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AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

AICR is committed to putting what we know about cancer prevention into action. To help you live healthier, we’ve taken the latest research and made 10 Cancer Prevention Recommendations.

Research Projects > 2018 Grantees

Mechanisms underlying the protective effect of exercise on primary mammary tumor growth and metastases: Role of metabolic and immune-mediated processes

Research Type: Breast Cancer

Project Description

This proposal will address the issue of the “dose” or amount of diet and exercise necessary to achieve a cancer prevention effect, specifically with respect to breast cancer prevention. Currently, it is not known how much exercise (dose, duration, frequency) or how much dietary restriction is needed for cancer prevention. Dr. Rogers and her team hypothesize that mild dietary restriction and increased physical activity will have additive effects to prevent breast cancer. They will use an animal model of breast cancer to test our hypotheses and study mechanisms. These studies will provide critical information about the amount of calorie reduction and physical activity necessary to achieve a cancer prevention effect.

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