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Research Projects > 2020 Grantees

Dietary folate intervention to modify recurrent prostate cancer progression

Research Type: Prostate Cancer

Project Description

Patients with metastatic prostate cancer generally undergo a treatment that has a high initial success rate, but then stops responding due to developing resistance. This project will test the hypothesis that resistance may develop due to high levels of circulating folate, and that a simple dietary intervention to decrease folate intake could help to decrease tumor proliferation. The primary aim of this study is to examine whether or not men undergoing treatment for metastatic prostate cancer have high levels of circulating folate, and whether or not folate has a substantial effect on the efficacy of the treatment.

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