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A major milestone in cancer research, the Third Expert Report analyzes and synthesizes the evidence gathered in CUP reports and serves as a vital resource for anyone interested in preventing cancer.

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AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

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Research Projects > 2010 Grantees

Dietary DIM in Pancreatic Cancer Prevention and Therapy

Project Description

This study is testing the hypothesis that the gene KLF4 plays a critical role in the ability of the dietary compound diindolylmethane (DIM) to prevent and repress tumor activity in pancreatic cancer. Experiments will determine how DIM affects the level and activity of KLF4 in pancreatic cancer cells and in mouse models, and provide information about whether other food components shown to activate KLF4 can be safely used for pancreatic cancer treatment.

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