When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

40 Years of Progress: Transforming Cancer. Saving Lives.

The AICR Lifestyle & Cancer Symposium addresses the most current and consequential issues regarding diet, obesity, physical activity and cancer.

The Annual AICR Research Conference is the most authoritative source for information on diet, obesity, physical activity and cancer.

Cancer Update Program – unifying research on nutrition, physical activity and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

Are you ready to make a difference? Join our team and help us advance research, improve cancer education and provide lifesaving resources.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

Research Projects > 2021 Grantees

Diet-microbiota-host interactions mediating anti-tumor immune responses in colorectal cancer

Research Type: Colorectal Cancer

Project Description

Colorectal cancer (CRC) is a leading cause of cancer death globally with increasing incidence in the developing world and a frightening trend towards earlier onset. CRC is strongly associated with environmental, lifestyle and dietary factors. Dr. Garrett’s research explores the interaction between diet and gut microbiota to identify new targets for CRC treatment and prevention.

They hypothesize that the role of gut bacteria in responsiveness to immunotherapies might reflect immune differences that can be used to promote effective anti-tumor immunity via diet. They will use human gut microbiome data from cancer patients, mouse models of CRC, immunotherapies, and specially designed diets to study this issue. The goal of this research is to safely, successfully, and rapidly apply these findings for cancer prevention and to aid in cancer treatment, with an initial focus on colorectal cancer.

More News & Updates