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AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

40 years of progress

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AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

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Research Projects > 1993 Grantees

Neural Cell Adhesion Molecule and Retinoic Acid Receptor Expression in Brain Tumors: Their Potential Roles in Metastasis and Adoptive Immunotherapy

Project Description

Neural cell adhesion molecule (NCAM) expression may be regulated by retinoic acid causing increased intercellular adhesion and a decreased ability for tumors to infiltrate the brain thereby decreasing potential metastatic tumors. Dr. Kruse examined the potential role of NCAMs in immunotherapy for astrocytomas and glioblastomas, two types of brain tumors.

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