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AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

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AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

Research Projects > 2026 Grantees

Impact of menopausal transitions and hormone levels on weight loss in premenopausal breast cancer survivors: A companion study to the Breast Cancer Weight Loss (BWEL) trial

Research Type: Breast Cancer

Project Description

Pre-menopausal women are at increased risk for weight gain after breast cancer compared to post-menopausal women. Obesity and weight gain after diagnosis are associated with poor outcomes for women with early onset breast cancer. This research will assess whether the onset of menopause, caused by the cancer treatment, is associated with greater weight gain and reduced weight loss. Dr Ligibel will assess menstrual patterns and hormone levels in pre-menopausal breast cancer patients, with overweight and obesity, who were enrolled in a weight loss intervention study. By understanding the reasons for weight gain after breast cancer in younger women, clinicians will be better able to counsel these patients on how to address this issue and inform development of future weight loss interventions more tailored to young women.

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