Research Type: Colorectal Cancer
Project Description
Multiple myeloma is a serious type of blood cancer that affects nearly 200,000 people worldwide. Even though treatments have improved, this cancer is still difficult to treat, especially when patients stop responding to current therapies. Scientists are now studying how exercise can strengthen the body’s immune system to fight cancer cells more effectively. Previous studies have shown that just one session of exercise can increase the number and strength of a rare type of immune cell called γδ (gamma-delta) T-cells in the body. Dr Baker’s project aims to use exercise to improve the function of γδ T-cells, which can attack and kill cancer cells, including multiple myeloma cells. Dr Baker will collect immune cells from healthy people before and after a short cycling workout and also collect cells from multiple myeloma patients and then grow and test these cells against different types of multiple myeloma cells in the lab.
