When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

The Annual AICR Research Conference is the most authoritative source for information on diet, obesity, physical activity and cancer.

The Continuous Update Project (CUP) is an ongoing program that analyzes global research on how diet, nutrition and physical activity affect cancer risk and survival.

A major milestone in cancer research, the Third Expert Report analyzes and synthesizes the evidence gathered in CUP reports and serves as a vital resource for anyone interested in preventing cancer.

AICR has pushed research to new heights, and has helped thousands of communities better understand the intersection of lifestyle, nutrition, and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

AICR is committed to putting what we know about cancer prevention into action. To help you live healthier, we’ve taken the latest research and made 10 Cancer Prevention Recommendations.

Research Projects > 1994 Grantees

Ascorbyl Esters as Antiglioma Agents: Mechanistic Study

Project Description

Dr. Kulkarni found that ascorbyl stearate, vitamin C, is a potent inhibitor of glutathione S-transferase and lipoxygenase, important enzymes for growth and proliferation of glioma (tumor) cells in culture. Screening ascorbyl derivatives as inhibitors of these enzymes in glioma cells in vitro, he sought to identify the most effective compounds for in vivo studies. Dr. Kulkarni’s long-term goal was to identify effective non-toxic therapeutic agents that can minimize drug resistance in tumor cells or act as antiglioma agents.

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