When you include the American Institute for Cancer Research in your estate plans, you make a major difference in the fight against cancer.

Corporate Champions who partner with the American Institute for Cancer Research stand at the forefront of the fight against cancer

The Continuous Update Project (CUP) is an ongoing program that analyzes global research on how diet, nutrition and physical activity affect cancer risk and survival.

A major milestone in cancer research, the Third Expert Report analyzes and synthesizes the evidence gathered in CUP reports and serves as a vital resource for anyone interested in preventing cancer.

Whether you are a healthcare provider, a researcher, or just someone who wants to learn more about cancer prevention, we’re here to help.

AICR has pushed research to new heights, and has helped thousands of communities better understand the intersection of lifestyle, nutrition, and cancer.

Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship.

We bring a detailed policy framework to our advocacy efforts, and provide lawmakers with the scientific evidence they need to achieve our objectives.

AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer.

AICR’s resources can help you navigate questions about nutrition and lifestyle, and empower you to advocate for your health.

AICR is committed to putting what we know about cancer prevention into action. To help you live healthier, we’ve taken the latest research and made 10 Cancer Prevention Recommendations.

November 4, 2013 | 2 minute read

How much weight do I need to lose in order to get health benefits?

Q:        How much weight do I need to lose in order to get health benefits?

A:        If you are overweight, losing at least five percent of your weight is what research identifies as “clinically meaningful.” That means it leads to changes big enough to matter for conditions such as high blood pressure, high cholesterol, triglyceride levels (a fat in the blood linked to heart disease risk), blood sugar control (in people with diabetes and pre-diabetes) and insulin resistance. A five percent weight loss translates to 13 pounds for someone who weighs 250 pounds, 10 pounds for someone who weighs 200, or 9 pounds for someone who weighs 180. Weight loss of 10 percent tends to produce even greater improvements in these health measures.
To reduce cancer risk, the lowest risk for several cancers is seen at the low end of what’s labeled a healthy BMI (body mass index). Cancer is a disease that develops over years, so risk is unlikely to change immediately with weight loss. However, since research shows that factors like elevated insulin levels that promote cancer decrease with even five percent weight loss, it seems reasonable to expect that cancer risk may change with relatively modest losses, too. In a large study of weight gain and loss in post-menopausal women, the most common pattern of body weight was a consistent increase throughout adulthood, and these women had the highest rates of breast cancer. Compared to this group, women who gained weight during some period of adulthood but then lost and maintained at least 5 percent of their body weight, decreased their risk of breast cancer by 20 percent or more. For any individual, the healthiest weight loss recommendations may vary, so do discuss this with your doctor. And remember that the benefit comes in losing excess fat – not lean muscle – and in maintaining whatever weight loss you achieve. During and after weight loss, focus on creating and maintaining a healthy new lifestyles.

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