Bad diet, inactivity, smoking and drinking alcohol - all are among the causes of up to 90 percent of cancers, according to a new analysis that stresses how many cases of cancer are under our control.\n\nThis paper, published\u00a0in Nature, is in stark opposition to the paper out earlier this year.\u00a0Published in\u00a0Science, that paper found that the majority\u00a0of cancer cases were caused by \u201cbad luck,\u201d our cells going awry without much people could do to control them. At that time, we pointed out some key flaws with their\u00a0analysis.\n\nThis study used the same premise and a lot of the same data as the Science article to reach a different conclusion: lifestyle makes a difference when it comes to cancer risk.\n\nHere at AICR, where we focus on how diet, physical activity and body fat link to cancer, a wide and consistent body of evidence shows that these factors make a difference. One third of the most common cancers can be prevented with diet, staying lean, and being active.\n\n\n\nAdd in not smoking, using sunscreen and other risk factors, and the number goes up even more.\n\nIn the Nature paper, the authors found that the\u00a0factors we can\u2019t control - the intrinsic factors - only influence less than 10 to 30 percent of the most common cancers. The other causes of cancer, the extrinsic factors that are under our control, are responsible for more than\u00a070\u00a0to\u00a090 percent of the most common cancer types.\n\nFor example, using different types of evidence, the paper finds\u00a0that about seven of every ten cases of colorectal cancers are due to such lifestyle factors as eating an unhealthy diet,\u00a0smoking, drinking alcohol and being overweight.\n\nLike the previous researchers, the authors of the Nature article looked at how cancer risk relates to the division of stem cells. These cells can develop into different types of cells in our body and the theory is, if they form mutations during these division it can lead to cancer. But they also looked at population studies, along with research that analyzed cancer mutations.\n\nThe work was supported by grants from the National Cancer Institute.