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Research Projects > 2005 Grantees

The Obesity-Cancer Link: Do Fatty Acids Promote the Tumorigenic Actions of IGF-1?

Project Description

The effects of two fatty acids, oleate and palmitate, on the actions of insulin-like growth factor (IGF)-1 in breast cancer cells and in non-malignant breast epithelial cells were examined. IGFs have been strongly implicated as an important risk factor for many common cancers, including breast, and fatty acids are increased in the blood of obese individuals and are known to cause resistance to the actions of insulin.

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