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New Report Highlights Potential Links Between
Weight, Physical Activity and Breast Cancer Survival

WASHINGTON, DC — For the first time, a report from an ongoing, systematic review of global cancer research has identified potential links between diet, weight and physical activity and longer survival for women diagnosed with breast cancer.

In partnership with the American Institute for Cancer Research (AICR), World Cancer Research Fund (WCRF) International’s Continuous Update Project (CUP) today released a report that found indications of links between survival and:

  • A healthy body weight
  • Being physically active
  • Eating foods containing fiber and soy
  • A lower intake of fat, particularly saturated fat

The latest report from the Continuous Update Project is the most rigorous, in-depth and systematic review of worldwide research yet conducted into breast cancer survivors and the lifestyle factors affecting their survival.

The CUP analysis includes 85 separate studies of 164,416 women and highlights growing evidence of links between a healthy BMI, physical activity, diet and all-cause mortality, breast cancer mortality, and subsequent primary breast cancer incidence.

The findings of Diet, Nutrition, Physical Activity and Breast Cancer Survivors support AICR’s recommendations that eating a plant-based diet, keeping to a healthy weight and getting regular physical activity remain the best strategies for all cancer survivors to follow. The report concludes, however, that currently available scientific evidence is still not strong enough to give concrete recommendations specifically for breast cancer survivors.

“Although it is difficult to make specific recommendations, the research suggests that women who have a healthy weight and are physically active, both before and after they are diagnosed, have a better chance of surviving a diagnosis of breast cancer and of not getting a second primary breast cancer,” said Anne McTiernan, MD, PhD, the panel lead of the CUP report and a researcher in the Public Health Sciences Division at the Fred Hutchinson Cancer Research Center in Seattle. “We need to know more about the effects of other factors on the associations between lifestyle and survival, including specific types of tumors, the stage at which a tumor is found, previous cancer treatment, and socio-economic factors.”

Previous reports from AICR and WCRF International have shown that a healthy body weight reduces the risk for eight cancers, including post-menopausal breast cancer.

Today’s report also found some evidence that women who eat more foods containing fiber and soy may have a lower risk of dying following a diagnosis of breast cancer, and that women eating a diet high in fat and saturated fat may have increased risk of dying following a diagnosis of breast cancer, although these findings are also still not strong enough to merit specific recommendations for breast cancer survivors.

“We know there are many reasons for women to eat a plant-based diet and be active, both for cancer prevention and overall health,” said Alice Bender, RDN, MS, AICR Associate Director for Nutrition Programs. “For survivors, start where you are and look for small changes you can make. For example, take advantage of the times you feel best to walk or move in some way. Use pre-chopped or frozen vegetables as an easy way to boost your healthy diet.”

Over 232,000 women are diagnosed with breast cancer in the US per year, and increasing numbers of women are surviving as methods of diagnosis and treatment improve. Over 3.1 million US women are currently breast cancer survivors.

In 2007, AICR and WCRF published an expert report that weighed the evidence linking various lifestyle factors to 20 different cancers, and released 10 Recommendations for Cancer Prevention. Since that time, the CUP has continued to monitor and analyze global research and draw conclusions about how diet, weight and physical activity affect the chances of developing various cancers. To date, new CUP Reports have reviewed the updated evidence on the prevention of breast, colorectal, pancreatic, endometrial and ovarian cancers. More reports will be published over the next three years; in 2017, AICR and WCRF International will release new, updated Recommendations for Cancer Prevention.

Today’s report on breast cancer survivors – the first CUP report to look at survivorship – has not changed AICR’s advice to the survivor community: After treatment, breast cancer survivors should follow AICR’s 10 Recommendations for Cancer Prevention, as guided by their health care professional.

Notes for Editors

  • For an advance copy of the full Breast Cancer Survivors CUP report, please visit our CUP Breast Cancer Survivorship section.
  • The report will be available beginning October 16th.
  • CUP panel members in the US include: Elisa Bandera MD PhD, Rutgers Cancer Institute of New Jersey; Steven Clinton MD PhD, Ohio State University; Edward Giovannucci MD ScD, Harvard School of Public Health; Stephen Hursting PhD MPH, University of North Carolina at Chapel Hill; and Anne McTiernan MD PhD, Fred Hutchinson Cancer Research Center.
  • The cancers linked to being overweight or obese are: ovarian, colorectal, post-menopausal breast, endometrial, esophageal, kidney, pancreatic and gallbladder.
    • Healthy weight = BMI of 18.5 to 24.9
    • Overweight = BMI of 25 to 29.9
    • Obese = BMI of 30 or more
  • There are several possible mechanisms to explain links between diet, weight, and physical activity with breast cancer prognosis. For example:
    • Being overweight or obese increases blood levels of insulin, estrogen and other hormones that can encourage the growth of cancerous cells. Because fat tissue is metabolically active, it produces proteins that cause inflammation, which can promote cancerous changes in cells and tissues.
    • Physical activity may influence breast cancer outcomes through its effects on hormones and by helping women prevent weight gain.

The American Institute for Cancer Research (AICR) is the cancer charity that fosters research on the relationship of nutrition, physical activity and weight management to cancer risk, interprets the scientific literature and educates the public about the results. It has contributed over $105 million for innovative research conducted at universities, hospitals and research centers across the country. AICR has published two landmark reports that interpret the accumulated research in the field, and is committed to a process of continuous review. AICR also provides a wide range of educational programs to help millions of Americans learn to make dietary changes for lower cancer risk. AICR is a member of the World Cancer Research Fund International (WCRF).

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