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Home Our Cancer Research Regulation of Colonocyte Growth and Differentiation
| Project Title: | Regulation of Colonocyte Growth and Differentiation |
| Research Institution: | Vanderbilt University School of Medicine |
| State, Country: | TENNESSEE |
| Researchers: | John A. Barnad III M.D. |
| Year: | 1994 |
| Project Description: | Dr. Barnard is investigating the mechanism by which butyrate exerts rapid and potent effects on growth and maturation of colon epithelial cells. This effect appears to be mediated through a key growth-rgulating gene c-myc. Dr. Barnard's studies will increase our understanding of the molecular mechanisms by which butyrate affects c-myc as well as the degree of maturation of the colon epithelial cells. |