The Role of Nuclear Hormone Receptors in PUFA-Mediated Modulation of Normal Brain and Glioma Cell Catalase Expression (1999)

Title:

The Role of Nuclear Hormone Receptors in PUFA-Mediated Modulation of Normal Brain and Glioma Cell Catalase Expression

Key words:

PUFAs, glioma

Research Institution:

University of Iowa

Location:

Iowa

Researcher:

Michael E Robbins

Project Description:

Dr. Robbins studied whether the ability of dietary polyunsaturated fatty acids (PUFA) to cause the death of brain tumor cells, specifically from gliomas, might be due to an increase in free radical formation, causing lower cell survival and greater radiosensitivity of the PUFA treated cells.