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Dietary Antioxidants, p53 status, and Tumorigenesis in a Wnt-1 mouse Model of Human Breast Cancer (1999)

Title:

Dietary Antioxidants, p53 status, and Tumorigenesis in a Wnt-1 mouse Model of Human Breast Cancer

Key words:

beta-carotene, tocopherols, reactive oxygen species, apoptosis

Research Institution:

University of North Carolina at Chapel Hill

Location:

North Carolina

Researcher:

Craig D Albright

Project Description:

Dr. Albright examined the opposing roles of dietary antioxidants, such as beta-carotene and tocopherols, versus reactive oxygen species in tumor apoptosis, using a transgenic mouse model that readily develops mammary tumors.

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