Effects of Chemotherapeutic Isoprenoids on the Mevalonate Pathway (1999)

Title:

Effects of Chemotherapeutic Isoprenoids on the Mevalonate Pathway

Key words:

dietary isoprenoids, geraniol, farnesol, mevalonate pathway

Research Institution:

Indiana University-Purdue University

Location:

Indiana

Researcher:

Pamela L Crowell

Project Description:

Dr. Crowell hypothesized that dietary isoprenoids such as geraniol or farnesol may exert antitumor effects in pancreatic tumor models through modulation of the mevalonate pathway in tumor cells, and thus depress the proteins that increase tumor cell growth.