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Role of p27 and cdk2 in Retinoid Regulation of Breast Cancer Cell Growth (1999)

Title:

Role of p27 and cdk2 in Retinoid Regulation of Breast Cancer Cell Growth

Key words:

retinoic acid, cell kinases

Research Institution:

University of Ottawa

Location:

Canada

Researcher:

M.A. Christine Pratt

Project Description:

Dr. Pratt investigated how retinoic acid (RA) inhibits the growth of hormone-dependent breast cancer cells (MCF-7), based on the hypothesis that RA decreases the levels of certain cell kinases and leads to hypophosphorylation of the kinase complexes.

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