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Increasing the Effectiveness of Bioreductive Antitumor Agents (1999)

Title:

Increasing the Effectiveness of Bioreductive Antitumor Agents

Key words:

DT-diaphorase enzyme, mitomycin C

Research Institution:

University of Manitoba

Location:

Canada

Researcher:

Asher Begleiter

Project Description:

Dr. Begleiter investigated how increased levels of the DT-Diaphorase enzyme (DTD) enhance the antitumor activity of chemotherapeutic agents such as mitomycin C, in addition to searching for diet-based enzyme inducers, which increase the activity of DTD.

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