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Pharmocodynamic Effects of Perillyl Alcohol in Humans (1997)


Pharmocodynamic Effects of Perillyl Alcohol in Humans

Key words:

perillyl alcohol, limonene, Ras protein, clinical trial

Research Institution:

University of Iowa




Raymond J Hohl

Project Description:

Dr. Hohl examined the role of perillyl alcohol, a metabolite of limonene, in decreasing the expression of Ras protein in patients in a clinical trial, presumably through inhibition of farnesyl- and geranylgeranyl protein transferases.

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