Cancer Chemoprevention by Curcumin: Mechanistic Studies (1995)

Title:

Cancer Chemoprevention by Curcumin: Mechanistic Studies

Key words:

curcumin, v-ras, v-fos, oncogenes, protein kinase C

Research Institution:

Chaing Mai University

Location:

Thailand

Researcher:

Porn-ngam Limtrakul

Project Description:

Dr. Limtrakul sought to determine whether dietary curcumin, a food seasoning, would inhibit skin carcinogenesis in animal models. To investigate the mechanism of action by which curcumin affects genetic changes in carcinogen-induced responsive genes, she studied the expression of v-ras and v-fos oncogenes and protein kinase C gene families in the mouse epidermis after treatment with different diets.