Therapy of Neuroblastoma with Retinoic Acid (1995)

Title:

Therapy of Neuroblastoma with Retinoic Acid

Key words:

neuroblastoma, retinoic acid

Research Institution:

Children's Hospital of Los Angeles

Location:

California

Researcher:

C. Patrick Reynolds

Project Description:

Dr. Reynolds examined the biology underlying the initial sensitivity and resultant resistance of neuroblastoma cells to retinoic acid. His investigations on the role of retinoic acid receptors and oncogene expression, transcription factors and protein phosphorylation will provide new insights into improving the response of tumors to retinoid treatment.