Retinoid Interference with Lung Tumor Promotion (1995)

Title:

Retinoid Interference with Lung Tumor Promotion

Key words:

BHTOH, retinoids, GJIC

Research Institution:

University of Colorado at Denver

Location:

Colorado

Researcher:

Alvin M Malkinson

Project Description:

Dr. Malkinson investigated the potential of retinoids to block the lung tumor promoting ability of butylated hydroxytoluene (BHT) metabolite BHTOH, and the effects of BHTOH on gap junction intercellular communication (GJIC), apoptosis and proliferation. In this study retinoid effects will be studied in a model of human adenocarcinoma.