Butyrate-mediated Signal Transduction in Colonocytes: Role of cAMP-dependent Protein Kinase (1995)

Title:

Butyrate-mediated Signal Transduction in Colonocytes: Role of cAMP-dependent Protein Kinase

Key words:

butyrate

Research Institution:

Texas A & M University

Location:

Texas

Researcher:

Harold M Aukema

Project Description:

Dr. Aukema investigatedthe diverse actions of butyrate, a major by-product of dietary fiber breakdown by bacteria in the colon, on cell proliferation. Using a unique colonic cell culture system, Dr. Aukema sought to determine the effect of butyrate under conditions seen with tumor cell cultures and under normal conditions to elucidate the potential anti-cancer properties of dietary fiber.