Induction of Iron-Metabolizing Enzymes by Dietary Chemopreventive Agents (1995)

Title:

Induction of Iron-Metabolizing Enzymes by Dietary Chemopreventive Agents

Key words:

iron, D3T, heme oxygenase, ferritin

Research Institution:

The Johns Hopkins University

Location:

Maryland

Researcher:

Thomas Primiano

Project Description:

Dr. Primiano investigated the induction of iron related enzymes and storage proteins, heme oxygenase and ferritin, by 1,2-dithiole-3-thione (D3T) in a hepatic cell line and sought to determine whether D3T alters iron homeostasis and reduces susceptibility to oxidative stress.