Inhibition of EGF Receptor Activation by Curcumin (1994)

Title:

Inhibition of EGF Receptor Activation by Curcumin

Key words:

curcumin, epidermal growth factor receptors,

Research Institution:

Hershey Medical Center

Location:

Pennsylvania

Researcher:

Rakesh Kumar

Project Description:

Curcumin, the major active yellow pigment of the spice turmeric, has been shown to have anti-proliferative properties in human tumor cell cultures. Dr. Kumar investigated the inhibitory effects of curcumin on carcinogen stimulation or activation of cellular and molecular pathways in MH3T3 cells. He also examined whether there is inhibition of mitogen-induced activation of epidermal growth factor receptors.