Dietary Choline Deficiency: Studies on the Early Events Leading to Hepatocarcinogenesis (1994)

Title:

Dietary Choline Deficiency: Studies on the Early Events Leading to Hepatocarcinogenesis

Key words:

choline deficiency, hepatocarcinogenesis

Research Institution:

University of North Carolina at Chapel Hill

Location:

North Carolina

Researcher:

Steven H Zeisel

Project Description:

Dr. Zeisel continued his investigations of the mechanism of hepatocarcinogenesis by dietary choline deficiency. He sought to determine if choline-deficient animals will undergo early sensitizing events and later gene damaging events leading to cancer. He also sought to identify other nutrients and drugs which block this process.