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Genotoxicity of Dietary Amines in the Pancreas (1994)

Title:

Genotoxicity of Dietary Amines in the Pancreas

Key words:

herterocyclic amines, fat

Research Institution:

Eppley Institute for Research in Cancer

Location:

Nebraska

Researcher:

Terence A Lawson

Project Description:

Dr. Lawson has shown that heterocyclic amines, formed by pyrolysis of foods high in protein and fat as well as by smoking tobacco, are mutagenic and carcinogenic in several animal systems. Mutagenicity was particularly significant in pancreatic cell studies. He further investigated these heterocyclic amines to determine their potential to induce pancreatic cancer.