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Effect of Mevinolin and Limonene on CT-26 Hepatic "Metastasis" in BALB/c Mice (1993)

Title:

Effect of Mevinolin and Limonene on CT-26 Hepatic "Metastasis" in BALB/c Mice

Key words:

limonene, mevacor, cholesterol

Research Institution:

Boston University

Location:

Massachusetts

Researcher:

Selwyn A Broitman

Project Description:

Dr. Broitman examined how limonene and a drug mevacor (mevinolin), which inhibits production of cholesterol in the liver, alter the functioning of a specific oncogene, ras-oncogene, and affect colon cancer development.

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