Zinc as an Activator of the Mitogenic Transactivation Factor c-Jun (1993)

Title:

Zinc as an Activator of the Mitogenic Transactivation Factor c-Jun

Key words:

c-Jun, zinc

Research Institution:

Veterans Medical Research Foundation of San Diego

Location:

California

Researcher:

Daniel A Mercola

Project Description:

c-Jun is a necessary protein for normal cell division. When cells go through normal cell division they can produce oncoproteins that promote mutations of the protein possibly leading to cancer. Applying excess zinc to normal cells in culture caused more cells than normal to transform to oncoproteins. Dr. Mercola looked at the effect excess zinc has on the transformation of the protein c-Jun.