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Retinoids, Papillomavirus and Cervical Cancer (1993)

Title:

Retinoids, Papillomavirus and Cervical Cancer

Key words:

human papillomavirus (HPV)

Research Institution:

Case Western Reserve University

Location:

Ohio

Researcher:

Richard L Eckert

Project Description:

Ninety percent of cervical cancers are associated with human papillomavirus (HPV). Vitamin A is known to regulate the function of the epithelial cells of the cervix and HPV cells are sensitive to vitamin A. In his renewal grant, Dr. Eckert sought to identify the gene responsible for retinoid sensitivity in the cells of the cervix in hopes of coming up with better and more effective treatment for this cancer.

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