Effect of Zinc Replenishment on Cell Proliferation and Esophageal Carcinogenesis in Zinc Deficient Rats (1993)

Title:

Effect of Zinc Replenishment on Cell Proliferation and Esophageal Carcinogenesis in Zinc Deficient Rats

Key words:

zinc deficiency

Research Institution:

Thomas Jefferson University

Location:

Pennsylvania

Researcher:

Louise Y Fong

Project Description:

In many areas of the world, the high rates of esophageal cancer are associated with vitamin and mineral deficiencies rather than tobacco and alcohol uses as in the United States. Dr. Fong studied the role of dietary zinc deficiency in esophageal cancer, in hopes of answering two questions: 1) is zinc deficiency reversible; and 2) does zinc prevent development of esophageal tumors in a carcinogen-induced (N-methylbenzylnitrosamine) model.