Dietary Influences on Reversal of Changes in DNA Methylation and Expression of Protooncogenes and Suppressor Genes Induced by Short-term Lipotrope Deficiency (1992)

Title:

Dietary Influences on Reversal of Changes in DNA Methylation and Expression of Protooncogenes and Suppressor Genes Induced by Short-term Lipotrope Deficiency

Key words:

lipotropes, folic acid, vitamin B12, choline, methionine, oncogenes

Research Institution:

Michigan Cancer Foundation

Location:

Michigan

Researcher:

Judith K Christman

Project Description:

Dr. Christman investigated how diets that are deficient in lipotropes, folic acid, vitamin B12, choline, and methionine, might increase the susceptibility to cancer-causing agents and enhance liver cancer. Her studies focused on hypomethylation of selected oncogenes.