Studies on the Possible Linkage Between the Delivery and Metabolism of Dietary Retinoid to Bone Marrow and Acute Promyelocytic Leukemia (1992)

Title:

Studies on the Possible Linkage Between the Delivery and Metabolism of Dietary Retinoid to Bone Marrow and Acute Promyelocytic Leukemia

Key words:

retinoic acid, retinol, beta-carotene, acute promyelocytic leukemia

Research Institution:

Columbia University

Location:

New York

Researcher:

William S Blaner

Project Description:

Dr. Blaner investigated whether all-trans retinoic acid, an active form of vitamin A, might be increased in circulation, bone marrow, and tissues by increasing the amounts of dietary retinol or beta-carotene and other forms of vitamin A during the treatment of acute promyelocytic leukemia (APL).