The Role of Nutritional Conditioning and Cellular Adaptation in the Genesis and Suppression of Neoplastic Transformation in Mouse Embryo NIH 3T3 Cells (1992)

Title:

The Role of Nutritional Conditioning and Cellular Adaptation in the Genesis and Suppression of Neoplastic Transformation in Mouse Embryo NIH 3T3 Cells

Key words:

glutamine

Research Institution:

University of California, Berkeley

Location:

California

Researcher:

Harry Rubin

Project Description:

Dr. Rubin investigated whether glutamine, a calorie-supplying amino acid, might suppress or reverse the spontaneous transformation of NIH 3T3 cells and whether glutamine restriction might elicit an adaptation and inheritable suppression of transformation in these cells.