Can Putative Preneoplastic Foci be Used to Evaluate Inhibitors of Colon Carcinogenesis (1989)

Title:

Can Putative Preneoplastic Foci be Used to Evaluate Inhibitors of Colon Carcinogenesis

Key words:

enzyme-altered foci, abberant crypts, selenium, phytate

Research Institution:

Case Western Reserve University

Location:

Ohio

Researcher:

Theresa P Pretlow

Project Description:

Dr. Pretlow sought to determine whether early changes in colon tissue, such as enzyme-altered foci and aberrant crypts, can be used to predict increased risk for colon cancer and whether selenium or phytate in fiber-rich foods can prevent the transition to colon cancer.