Dietary Induction of Nucleotide Imbalance and Promotion of Carcinogenesis (1985)

Title:

Dietary Induction of Nucleotide Imbalance and Promotion of Carcinogenesis

Key words:

orotic acid, milk, arginine

Research Institution:

UMDNJ-New Jersey Medical School

Location:

New Jersey

Researcher:

Michael A Lea

Project Description:

Dr. Lea studied if a compound found in milk, called orotic acid, can, in high concentrations, promote the development of kidney cancer by interfering with the normal synthesis of DNA. In addition, the possibility that a diet deficient in arginine, an essential amino acid, might act in a similar fashion was investigated.