Magnesium, Calcium, and Risk for Colorectal Adenoma (2008)

Title:

Magnesium, Calcium, and Risk for Colorectal Adenoma

Key words:

calcium, magnesium, TRPM7 gene, Tennessee Colorectal Polyp Molecular Epidemiological study

Research Institution:

Vanderbilt University

Location:

Tennessee

Researcher:

Qi Dai

Project Description:

This study proposed that calcium magnesium ratio infuences the risk of developing colonic adenomas and that polymorphism associated with TRPM7 gene augments the risk. In this molecular epidemiological study, the samples were collected from an ongoing Tennessee Colorectal Polyp Molecular Epidemiological Study. Urinary and erythrocyte calcium and magnesium levels were measured in 300 cases and controls, and TRPM7 polymorphism analyses were carried out on 2000 cases and controls each.