Dietary Folate Manipulation: Impact on Prostate Tumor Biology, Genetics and Epigenetics (2007)

Title:

Dietary Folate Manipulation: Impact on Prostate Tumor Biology, Genetics and Epigenetics

Key words:

Folate, DNA damage

Research Institution:

Roswell Park Cancer Institute

Location:

New York

Researcher:

Gaia Bistulfi

Project Description:

This study examined how folate status in mammals affects epigenetic events that drive tumorigenesis in prostate epithelium. It aimed to determine if supplementation of folate slows the progression of prostate cancer from a harmless overgrowth to a lethally aggressive cancer, and if folate depletion increases the DNA damage.